AI / ML Engineer Jobs in St. Louis

1 positions available in MO. Midwest manufacturing and biotech hub with 210K+ software, biotech, and aerospace roles

Senior Machine Learning Engineer - Model Evaluations, Public Sector

Scaleai • San Francisco, CA; St. Louis, MO; New York, NY; Washington, DC

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Related Roles in St. Louis

Backend Developer Mobile Developer Product Manager Scrum Master

AI / ML Engineer in Other Cities

Las Vegas (NV) Cleveland (OH) Cincinnati (OH) Sacramento (CA)

What Does a AI / ML Engineer Do?

AI/ML engineers develop machine learning models and AI systems that learn from data to make predictions or decisions. They work on model architecture, training, optimization, and deployment to production systems.

AI / ML Engineer Salary in St. Louis

The median salary for a AI / ML Engineer in St. Louis is $97,218 per year. The range is $73K - $128K (P10: $54,909, P90: $166,113). (BLS OEWS 2025) Typical US salary range: $110K - $180K. In Europe: €75K - €120K. Cost of living in St. Louis is low compared to other cities.

Most In-Demand Skills

Python TensorFlow/PyTorch Machine Learning Theory NLP/Computer Vision Model Optimization LLM Fine-tuning

The St. Louis Job Market

Midwest manufacturing and biotech hub with 210K+ software, biotech, and aerospace roles. St. Louis's aerospace dominance and biotech sector offer stable, well-paid tech roles in one of America's most affordable cities.

Top industries: Aerospace & Defense, Biotechnology, Software, Finance.

Metro transit covers downtown; aerospace and tech companies support remote work for distributed teams.

Career Path & 2026 Trends

AI/ML engineers advance to senior ML engineer, research engineer, or ML platform architect; many pursue specialization in specific domains like NLP or computer vision. AI/ML engineering in 2026 is dominated by generative AI, with massive demand for engineers who can fine-tune and deploy LLMs in production environments.

Interview Tip

Walk through your model development lifecycle—discuss data preparation, model selection, hyperparameter tuning, and evaluation metrics that matter for the business.

How to Find a AI / ML Engineer Job in St. Louis?

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