Software Engineer, Frontier AI Infrastructure
Scaleai • San Francisco, CA; St. Louis, MO; New York, NY; Washington, DC
onsite
Software Engineer Jobs in St. Louis
5 positions available in MO. Midwest manufacturing and biotech hub with 210K+ software, biotech, and aerospace roles
Software Engineer, ARC Team
Scaleai • San Francisco, CA; St. Louis, MO; New York, NY; Washington, DC
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Start My Free SearchSenior Software Engineer, Public Sector
Scaleai • San Francisco, CA; St. Louis, MO; New York, NY; Washington, DC
onsite
Mission Software Engineer, Public Sector
Scaleai • Baltimore, MD; Colorado Springs, CO; Hampton Roads, VA; Tampa, FL; Tucson,AZ; San Francisco, CA; New York, NY; Honolulu, HI, St. Louis, MO; Washington, DC
hybrid
Mission Software Engineering Manager, Public Sector
Scaleai • San Francisco, CA; St. Louis, MO; New York, NY; Washington, DC
hybrid
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What Does a Software Engineer Do?
Software engineers design, develop, and maintain applications and systems using programming languages and software design principles. They work on everything from small utilities to large-scale distributed systems, often collaborating with cross-functional teams.
Software Engineer Salary in St. Louis
The median salary for a Software Engineer in St. Louis is $108,657 per year. The range is $78K - $139K (P10: $59,292, P90: $178,065). (BLS OEWS 2025) Typical US salary range: $90K - $160K. In Europe: €60K - €100K. Cost of living in St. Louis is low compared to other cities.
Most In-Demand Skills
System Design
Data Structures & Algorithms
Python/Java/Go
Version Control
Testing
Problem Solving
The St. Louis Job Market
Midwest manufacturing and biotech hub with 210K+ software, biotech, and aerospace roles. St. Louis's aerospace dominance and biotech sector offer stable, well-paid tech roles in one of America's most affordable cities.
Top industries: Aerospace & Defense, Biotechnology, Software, Finance.
Metro transit covers downtown; aerospace and tech companies support remote work for distributed teams.
Career Path & 2026 Trends
Software engineers advance to senior engineer, staff engineer, or engineering manager roles, with staff positions typically requiring 8-10 years of experience. Software engineering demand is exceptionally strong in 2026, with AI integration and cloud-native development becoming table-stakes.
Interview Tip
Focus on explaining your thought process during technical interviews—walk interviewers through your approach to problem-solving rather than just the final solution.
How to Find a Software Engineer Job in St. Louis?
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